Abstract
Background: liver metastases are a common site for metastatic disease, little is known about how frequently different malignancies manifest as liver metastases.Aim: To identify the most prevalent primary tumors and assess the effects of therapy and primary tumor detection on patient survival.Patients and Methods: This prospective study comprised 42 patients initially presenting with hepatic metastases of unknown primary origin at Mosul Oncology Hospital between 2018 and 2021. A thorough clinical and diagnostic evaluation was done to know the primary tumors, and the patient's ultimate diagnosis and survival were prospectively analyzedResults: Gastrointestinal tumors were found to be the most frequent primary tumors that metastasize to the liver followed by lung and breast cancer, patients with primary breast cancer had better survival compared with other primary that metastasize to the liver.Conclusion: The most common primary tumors that metastasize to the liver are gastrointestinal tumors, followed by lung and breast cancer. Because the prognosis of hepatic metastasis varies depending on the primary tumor, it is highly advised to undergo a thorough clinical, radiological, and pathological examination to identify the primary tumors. This will allow more tumor-specific treatment to be administered.
