Abstract
ABSTRACT
Objectives: To use a panel of seven tumor markers for the detection and follow up of colorectal cancer. To compare the diagnostic utility of the tumor markers with that of the standard methods. To construct ROC curve for the purpose of the best detection of the studied cancer.
Patients and methods: Fifty two colorectal cancer patients and 30 apparently healthy individuals as a control group were studied. They were tested for: carcinoembryonic antigen (CEA), cancer antigen 19-9, cancer antigen 72-4 and tissue polypeptide antigen (TPA), two cytokines [interleukin-6 (IL-6)] and vascular endothelial growth factor (VEGF)] by using ELISA. Twenty colorectal cancer patients were followed up for a period of 3-5 months after surgical resection.
Results: There was a significant difference (p
