Efficacy of Urine Cytology in the Detection of Bladder Urothelial Carcinoma: A Retrospective Study in Medical City-Baghdad
Annals of the College of Medicine, Mosul,
2021, Volume 43, Issue 1, Pages 10-15
To make a cyto-histological correlation and to evaluate the diagnostic efficacy of urine cytology in routine
Materials & methods:
From January 2015 to June 2020, one hundred and thirty-nine cases have been included in this case series retrospective study. Subjects were collected from the Ghazi al-Hariri Surgical Specialties Hospital, Medical City, Baghdad, Iraq. Ranging in age from fourteen to eighty-six years, presented most frequently with hematuria, or diagnosed radiologically with bladder tumor, who underwent cytological examination with the histological examination at the same time or within one year.
Patients were mostly between sixty-one and seventy years old (36.7%). The studied group was made of male (61.2%) and female (38.8 %).
Fifty-five patients who were diagnosed as negative/ benign in cytology examination, and histological examination at the same time, eight patients were diagnosed as high-grade urothelial carcinoma when they were diagnosed negative/ benign in the cytological examination, four patients were diagnosed negative in the histological examination when they were reported as high-grade urothelial carcinoma in the cytological exam, thirty-four patients were reported as high-grade urothelial carcinoma, cytologically and histologically. The sensitivity of high-grade urothelial carcinoma detection in suspicious or malignant cases in urine cytology was (80.95%), while the specificity (92.98%). the positive predictive value was (89.47%) when the negative predictive value was (86.88%).
It has always been known that urine cytology is a powerful and effective method for the screening of urothelial carcinoma; specifically, for high-grade urothelial carcinoma, and in the follow-up of patients after surgery or cystoscopy.
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