Main Subjects : Microbiology
Detection of Toxoplasma gondii and Herpes simplex IgM antibodies in frequently aborted women during different seasons in Mosul city
Annals of the College of Medicine, Mosul,
2020, Volume 42, Issue 1, Pages 57-61
Background: Many women suffer from frequent abortions due to many causes; one of these causes is infection with different types of microorganisms. Toxoplasma gondii protozoan and Herpes simplex virus (HSV) are well-known causes of repeated abortion. However, it is unclear whether seasonal changes could affect the re-activation of latent infections with these microorganisms.
Objectives: To detect the percentage of active toxoplasmosis and HSV infections among frequently aborted women, and evaluate seasonal changes on such active infection.
Patients and method: Two hundreds women with frequent abortions were tested for anti-toxoplasma gondii IgM antibodies and anti-HSV IgM antibodies in two different seasons (100 patients in summer and 100 patients in winter) and were compared for variance.
Results: For toxoplasmosis, only 2% of studied women were positive for IgM antibodies in winter in comparison to 3% in summer with a total active infection of 2.5% in both seasons; however, for HSV about 12% were positive in winter and 10% were positive in summer with a total active infection of 11% in both seasons.
Conclusion: Seasonal variance showed no significant change on re-activation of latent infection of both Toxoplasma gondii and HSV in frequently aborted women. The rate of infection in frequently aborted women with HSV is higher than the rate of infection with Toxoplasma gondii in Mosul city.