Print ISSN: 0027-1446

Online ISSN: 2309-6217

Main Subjects : Biochemistry


Obesity, adipose tissue types and adipocytokines

Nuha Shareef; Maryam Hani Abduljalal

Annals of the College of Medicine, Mosul, 2020, Volume 42, Issue 2, Pages 177-183
DOI: 10.33899/mmed.2020.128256.1045

The prevalence of obesity has increased worldwide in the last 50 years, reaching pandemic levels. The etiology of obesity is multifactorial, involving a complex of interaction among genetics, hormones and the environment. The adipose tissue plays a central role in regulating whole body energy. In one hand, the adipose tissue stores energy in the form of lipid and controls the lipid mobilization and distribution in the body, and on the other hand, adipose tissue acts as an endocrine organ and produces numerous bioactive factors such as adipocytokines. Moreover, brown and beige adipose tissue burn lipid by dissipating energy in the form of heat to maintain euthermia and have been considered as a new way to counteract obesity. In this review, we will summarize the recent findings of the types of adipose tissue and their role in controlling metabolism, focusing on its endocrine function. This review describes the molecular actions and clinical significance of the some important adipocytokines.

The assessment of glycemic control and renal function in ischemic heart patients

Ehsan Hassan Aldabbagh; Akram Ahmad

Annals of the College of Medicine, Mosul, 2020, Volume 42, Issue 1, Pages 27-34
DOI: 10.33899/mmed.2020.127368.1036

Abstract:
Background: Ischemic heart diseases are considered as the leading cause of death throughout the world and a major cause of hospital admissions. Diabetes mellitus together with hypertension are among the modifiable risk factors.
Aims of the study: To assess the glycemic control and renal function tests of patients with ischemic heart diseases.
Methods: Fasting blood samples were obtained from seventy one cases of ischemic heart disease who were admitted to cardiac care unit, mean age 60.9 years old, sera were used to measure urea, creatinine and glucose by enzymatic colorimetric method while blood with anticoagulant used for glycated hemoglobin measurement by ion exchange resin quantitative colorimetric determination and urine samples were obtained for analysis of protein/creatinine ratio by turbidimetric method. Measurement of micro albumin in urine is based on immunoassay with flouresence detection.Statistics included t-test and linear regression.